Jan-Hendrik Hardenberg is board certified in internal medicine and is a fellow in nephrology at Charité – Universitätsmedizin Berlin. He is interested in how digitalisation and the resulting abundance of data can be leveraged for clinical trials, particularly in how pragmatic trials could be run entirely on digitally extracted routine data. He is part of the team behind the Charité Outcomes Research Repository, CORR, which turns routine intensive care and perioperative data into validated, reusable clinical concepts for retrospective studies, prospective trials and bedside applications.

Clinically, his focus is on critically ill patients: electrolyte disorders, and how to optimise the delivery of kidney replacement therapy in the intensive care unit.

Philipp Enghard, MD, is Deputy Director of the Department of Nephrology and Intensive Care Medicine at Charité – Universitätsmedizin Berlin, Campus Mitte, where he also holds an apl professorship and leads his own research group. Board-certified in both nephrology and intensive care medicine, he splits his time between the clinic and the lab, with a research focus on acute kidney diseases and trials.

Beyond the clinic, Philipp chairs the German Society of Nephrology's Commission for Nephrological Intensive Care Medicine. He's also known for taking a playful approach to medical education, co-creating games like the "Antibiotics Quartet," and he coordinates a global health partnership investigating unexplained chronic kidney disease in Sri Lanka. He is committed to science, ICU-nerd enthusiasm and openness to any novel idea.

Frederique Paulus is Professor of Quality of Intensive Care at Amsterdam UMC and Professor of Critical Care at the Amsterdam University of Applied Sciences. She is an ICU nurse, clinical epidemiologist and senior researcher, with a particular interest in the care of invasively ventilated critically ill patients.

Her research focuses on mechanical ventilation and airway care, the evaluation of nursing interventions, and the implementation and de-implementation of evidence-based practices in critical care. She has led and contributed to several large multicentre studies examining ventilation strategies, airway care and other aspects of ICU practice. Her work aims to improve the effectiveness, safety and quality of intensive care, with particular attention to the role of ICU nurses in research and clinical care.

Siebe Blok is a pulmonology resident and PhD candidate in Intensive Care Medicine at Amsterdam UMC. He has a background in biomedical sciences and immunology. His research focuses on fluid management, mechanical ventilation and point-of-care ultrasound in critically ill patients, with a particular interest in translating physiological and biological concepts into clinical research.

He has coordinated several multicentre studies in critically ill patients. His work focuses on understanding variation in clinical practice and identifying opportunities to improve fluid and respiratory management in the intensive care unit.

Bruno Besen, M.D., MSc (CT), PhD. is a proud intensivist based in São Paulo, Brazil. He is an associate professor of Critical Care Medicine at Universidade Federal de São Paulo and holds an appointment as a researcher at Hospital Sírio-Libanês and IDOR Research Institute. He is an active member of the scientific and executive committee of the Brazilian Research in Intensive Care network (BRICnet) and the current president of the Education Committee of the Brazilian Critical Care Medicine Association (AMIB).

His main research interests include airway management in critically ill patients, sepsis, tracheobronchitis/pneumonia and infection in the ICU setting, and management of neurocritical care patients. He is one of the investigators on the IMPACTO-MR research platform, a registry-embedded platform for conducting individual- and cluster-randomized trials. His research activities are currently focused on comparative effectiveness clinical trials and high-quality observational studies to inform policy, practice, and further research. He is currently the recipient of an early-career development award from the Brazilian National Council for Scientific and Technological Development (CNPq) to support his research activities.

Twitter:  @BensenBruno

Bruno Tomazini, M.D. is a devoted father and husband who also happens to be an intensivist at Hospital Sírio-Libanês and a researcher at Hospital Sírio-Libanês and HCor Research Institute in São Paulo, Brazil. He is an active member of the scientific and executive committees of the Brazilian Research in Intensive Care Network (BRICNet).

His main research interests are sepsis and infection management in critically ill patients, with a particular focus on hemodynamic optimization and antimicrobial therapy. He is one of the investigators of the IMPACTO-MR research platform, a registry-embedded platform for individual- and cluster-randomized trials. His work centers on conducting clinical trials and multisource data acquisition to support observational studies and nationwide epidemiological surveillance of multidrug-resistant bacteria and antibiotic consumption.

Twitter:  @ICURevisited

Dr. Stoppe, a Professor of Anesthesiology and Intensive Care Medicine at Charité – Universitätsmedizin Berlin and Würzburg University in Germany, leads several international clinical trials in the field of clinical nutrition. He has established a global clinical research group dedicated to interventional nutrition studies in collaboration with partners worldwide.

The recipient of numerous research grants—including awards from the German Research Foundation (DFG) and other third-party funders—Dr. Stoppe’s research spans nutrition studies, perioperative optimization, functional outcomes and risk assessment, guideline development, translational research, and organ protection. His work focuses particularly on cardiac surgery, severe burns, and critically ill patients.

With more than 290 publications to his name, Dr. Stoppe is a frequent speaker at international conferences. He serves as Section Chair of the Feeding, Rehabilitation, Endocrinology & Metabolism section within the European Society of Intensive Care Medicine. Additionally, he contributes to and coordinates several European, American, German, and Canadian guideline initiatives and holds a position on the executive board of the ERAS Cardiac Society.

Twitter: @CStoppe

Marion Campbell is Vice-Principal (Research) for the University of Aberdeen and Professor of Health Services Research in the Health Services Research Unit (HSRU).   Marion is a medical statistician and clinical trialist. Her main research interests are in the design, conduct and analysis of clinical trials, especially complex trial design and the design and conduct of surgical and device trials.  She has published widely on clinical trials methodology, including on cluster randomised trials, design of trials of non-pharmacological interventions, pragmatic trials and trials reporting.  She has served on many national and international funding agencies and committees and is an elected Fellow of the Royal Society of Edinburgh, the Faculty of Public Health and the International Society for Clinical Trials.

Marion graduated with an honours degree in Statistics from the University of Aberdeen and subsequently gained an MSc in Statistics and PhD in Public Health.  Following early career appointments within the National Health Service in the fields of Operational Research and Statistics of Medical Audit, she joined the Health Services Research Unit in 1993.  She became Director of the Unit in 2007 - a position she held until the end of 2015, when she became Dean of Research for Life Sciences and Medicine.  She took up the role of Vice-Principal (Research) in October 2017.  HSRU remains her academic base.

Twitter:  @MarionKCampbell

Victoria Cornelius is a Professor in Medical Statistics and Trial Methodology and Director of Imperial Clinical Trials Unit. Her work in trials includes evaluating drug and complex interventions developing approaches that promote statistical efficiency in both Bayesian and frequentist frameworks. Her statistical methods research is in the use of time-to-event signal detection methods to identify adverse drug reactions, and co-leads the NIHR MRC TMRP specialist research group to improve the analysis of harm outcomes in randomised controlled trials.

Twitter:  @VR_Cornelius